# telos rx vs Rx.com: GLP-1 Weight Loss Compared **By TelosRX Editorial Team** · 2026-09-30 **Choosing between [telos rx](https://telosrx.com) and Rx.com for GLP-1 weight loss is closer than most comparisons. Both start compounded semaglutide at $99 a month, both are LegitScript-certified, and both hold the price flat as your dose rises. telos rx is lower on tirzepatide and adds needle-free and microdosed options. Rx.com brings a much broader healthcare catalog and a free prescription discount card.** The short answer **On semaglutide it is a tie at $99 a month, so do not let anyone tell you otherwise.** telos rx pulls ahead on tirzepatide, at $139 against $149, and on format, with a needle-free oral GLP-1 and a microdosed protocol that Rx.com does not offer. Rx.com is the better fit if you want weight care, a discount card and other prescriptions under one roof. [Start your intake →](https://start.telosrx.com/start-online-visit/weightloss) ## Quick comparison: telos rx vs Rx.com Feature telos rx Rx.com Compounded semaglutide As low as $99 per month $99 per month on its 12-month plan ($1,188 paid once); $175 month to month Compounded tirzepatide ✓ As low as $139 per month $149 per month on its 12-month plan ($1,788 paid once); $285 month to month Needle-free option ✓ Oral GLP-1, from $9 a day Injection only Microdosed option ✓ As low as $116 per month Not publicly listed Same price at every dose Yes Yes Visit format ✓ Fully asynchronous, no appointment Online questionnaire; some states add a short video visit Provider review ✓ Often within hours Usually within 24 hours Shipping ✓ Free 2-day Free; policy lists 2 to 4 business days to fill, then 3 to 7 to deliver Quarterly labs ✓ Included Not publicly listed Renewals Cancel anytime, no fee ✓ No automatic renewal; refills ship only after you check in Wider catalog and discount card Weight care plus peptides ✓ ED, hair, skin, hormones, women's health, plus a free pharmacy discount card Pharmacy and providers named Yes, in our FAQ Yes, Manifest Pharmacy and MD Integrations LegitScript Certified Displays a LegitScript seal Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider. Figures for both companies reflect publicly published pricing at the time of writing and can change. ## What is telos rx? telos rx is an online-first, asynchronous telehealth service for weight management. You complete a short intake of about five minutes. A US-licensed provider reviews it without a scheduled appointment, often within hours. The program is built around compounded GLP-1 medication. That includes compounded [semaglutide](https://www.telosrx.com/pages/semaglutide) and compounded [tirzepatide](https://www.telosrx.com/pages/tirzepatide), prepared by partner compounding pharmacies in the United States. Compounded medication is not FDA-approved. Pricing is published before you sign up. Your plan includes free 2-day shipping if approved, unlimited care-team messaging, quarterly labs, and dose adjustments as your body responds. You can cancel anytime with no fee, and you pay nothing if a provider declines you. Plans are FSA and HSA eligible, and telos rx is LegitScript-certified. Want to know what a provider would recommend for you? [Start your online visit](https://start.telosrx.com/start-online-visit/weightloss) and find out in minutes. ## What is Rx.com? Rx.com is a bigger and broader business than a typical GLP-1 brand. It started in prescription savings. Its free discount card and drug price search cover more than 60,000 US pharmacies, and that is still a core part of the site. It now describes itself as a full-stack healthcare platform. Alongside savings tools, it offers online care for weight loss, ED, hair loss, skin care, testosterone and women's health. It also links out to online therapy through a partner, and sells a low-cost price-tracking add-on called Rx Plus. The GLP-1 weight loss program is one line within that catalog, and the site labels it new. Rx.com is clear about how it is set up. It describes itself as a marketplace platform that connects patients with independently licensed providers, and it states that it does not dispense medication itself. That transparency deserves credit. Rx.com names its provider network, MD Integrations, and its dispensing pharmacy, Manifest Pharmacy in South Carolina, on its own pages. It displays a LegitScript seal. Many brands in this category name neither. One practical note, because the names are easy to mix up. Rx.com's own FAQ states that it is a separate, unaffiliated company from RxPros. If you are an RxPros patient, Rx.com cannot see your account. ## Medications: what each program offers Both services are built on the same two molecules. Semaglutide is a GLP-1 receptor agonist. Tirzepatide acts on two receptors, GLP-1 and GIP. A provider decides which, if either, is appropriate for you. The compounded versions offered by both telos rx and Rx.com are not FDA-approved. Rx.com says so plainly on its program pages, which is good practice. For background on this medication class, see the [NIH NIDDK overview of prescription weight-management medication](https://www.niddk.nih.gov/health-information/weight-management/prescription-medications-treat-overweight-obesity) and the [FDA overview of drug compounding](https://www.fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers). Rx.com sells both molecules as a once-weekly injection only. Its semaglutide dose range runs from 0.25 mg to 2.4 mg, and its tirzepatide range runs from 2.5 mg to 15 mg. Syringes, alcohol pads and a dosing guide are included. telos rx offers the injections too, and adds two formats Rx.com does not publish. The first is a needle-free [oral GLP-1](https://www.telosrx.com/pages/oral-tirzepatide), which dispenses oral semaglutide or oral tirzepatide at the clinician's discretion. The second is a lower-dose [microdosed tirzepatide](https://www.telosrx.com/pages/microdosed-tirzepatide) protocol, for people who want a gentler start. Format matters more than it sounds. GLP-1 medication only helps if you keep taking it. Two common reasons people stop are needle aversion and side effects while the dose climbs. A needle-free option addresses the first, and a microdosed protocol gives a provider another route for the second. **Key takeaway:** Same two compounded molecules, same $99 semaglutide entry point, and flat pricing at every dose on both sides. telos rx is $10 lower on tirzepatide and adds needle-free and microdosed formats. Rx.com wins on breadth and on its no-auto-renew refill model. ## Pricing, read carefully Both services publish their prices before you pay, which makes this easy to check. Here is what telos rx publishes: - Compounded semaglutide, as low as $99 per month. - Microdosed tirzepatide, as low as $116 per month. - Compounded tirzepatide, as low as $139 per month. - Needle-free oral GLP-1, from $9 a day. Rx.com prices by plan length, and it bills each plan in one payment. These are the figures on its own checkout page: - Compounded semaglutide: $99 a month on 12 months ($1,188), $146 on 6 months ($875), $165 on 3 months ($495), or $175 for a single month. - Compounded tirzepatide: $149 a month on 12 months ($1,788), $259 on 6 months ($1,550), $265 on 3 months ($795), or $285 for a single month. So the $99 headline is real, and we will not pretend otherwise. It matches our semaglutide price exactly. On Rx.com it is the 12-month rate, paid as one upfront amount of $1,188. If you would rather pay for one month at a time, Rx.com semaglutide is $175. On tirzepatide, telos rx is as low as $139 a month against Rx.com's lowest rate of $149. That is a modest gap, but it is a real one. Two things Rx.com does well on price deserve a clear mention. Its rate does not rise with your dose, and it says so in plain language. It also includes the provider visit, supplies, cold-packed shipping and care-team messaging in the price, with no separate membership fee. telos rx also holds a flat price through titration, so that part is parity. One small inconsistency is worth knowing about. An older Rx.com program page still shows higher first-month and follow-on prices. The main weight loss page and the checkout both show the lower plan prices above, so we used those. If you see two numbers, go by the one at checkout. Want to see your own figure? [Start your intake](https://start.telosrx.com/start-online-visit/weightloss) and a provider will review it. ## How the process works With telos rx, you complete a roughly five-minute intake online. You share your health history, current medication and goals. A US-licensed provider reviews it asynchronously, often within hours, with no call to book. If approved, your medication ships free with 2-day delivery. With Rx.com, you answer a short pre-qualification quiz, choose a medication and plan, and check out. You then complete a health questionnaire and upload a photo ID. A licensed provider in your state reviews your visit, usually within 24 hours. Some states add a short video visit. Rx.com takes payment before the provider review, but it states you are not charged for medication if you are not prescribed. Its refund policy adds that you get a full refund if a provider decides treatment is not clinically appropriate. That is a fair, clearly written policy. Delivery timing differs. Rx.com's refund and shipping policy says prescriptions typically ship 2 to 4 business days after approval, with delivery in 3 to 7 business days. telos rx ships free 2-day after approval. Rx.com lists service in 49 states, every state except Alaska, in its program FAQ. Some banners on the site say all 50 states, so check your own state during intake. Asynchronous is worth defining clearly. It means no scheduled call and no video visit. You submit your information, a provider reviews it on their own time, and the decision comes back to you. Either way, any prescription is subject to medical approval by a licensed provider. ## Support after you start telos rx includes unlimited care-team messaging, dose adjustments and quarterly labs in the plan price. The clinical relationship continues after the first shipment, and you are not charged extra to ask a question. Rx.com includes ongoing check-ins, dose adjustments and unlimited messaging with its care team. It also lists 24/7 customer support on its plans. It does not publish details of lab monitoring, so count labs there as not publicly listed rather than absent. The refill model is where Rx.com stands out. Its plans do not renew automatically. Before each refill the care team checks in, and nothing ships or is charged until you confirm. For anyone who has been caught out by a silent renewal elsewhere, that is a genuine comfort. If included lab work matters most to you, telos rx names it explicitly. [Begin your online visit](https://start.telosrx.com/start-online-visit/weightloss) when you are ready. ## Safety and disclosure Both programs are provider-gated. A licensed provider reviews your history before anything is prescribed, and both publish that clearly. Rx.com also publishes a detailed safety section on its weight loss page, including the boxed thyroid warning. GLP-1 medication is not right for everyone. Providers screen for a personal or family history of medullary thyroid cancer and multiple endocrine neoplasia syndrome type 2. They also screen for past pancreatitis, and for pregnancy or breastfeeding. Common early side effects include nausea and other digestive symptoms, which often ease as the body adjusts. Share your full health history at intake so your provider can make a safe call. telos rx includes quarterly labs to support that oversight over time. ## Which service is right for you? Recommended telos rx Best if you want a dedicated weight program with a lower tirzepatide price, needle-free and microdosed options, quarterly labs, and a fully asynchronous review with no appointment to book. Rx.com Best if you are happy with a weekly injection, want other prescriptions and a pharmacy discount card in the same place, and like refills that wait for your confirmation. For most people choosing a GLP-1 program on format and flexibility, telos rx is the stronger pick. If semaglutide by injection is all you need and you value one account for everything, Rx.com is a credible choice. [Start your treatment →](https://start.telosrx.com/start-online-visit/weightloss) Prefer to avoid injections altogether? [Start an oral GLP-1 visit](https://start.telosrx.com/start-online-visit/oral-glp) instead, or compare every format on our [GLP-1 options page](https://www.telosrx.com/pages/glp-1-options). ## Frequently Asked Questions ### Is Rx.com cheaper than telos rx? On semaglutide it is a tie at $99 a month. Rx.com's $99 is its 12-month rate, paid once as $1,188, and its single-month price is $175. On tirzepatide, telos rx is as low as $139 a month against Rx.com's lowest rate of $149. ### Is Rx.com legitimate? Rx.com displays a LegitScript seal on its site. It names its provider network, MD Integrations, and its dispensing pharmacy, Manifest Pharmacy. It describes itself as a marketplace that connects patients with independently licensed providers. telos rx is also LegitScript-certified. ### Does Rx.com offer a needle-free GLP-1? Not according to its own site. Rx.com lists compounded semaglutide and compounded tirzepatide as once-weekly injections only. telos rx offers a needle-free oral GLP-1 from $9 a day, which dispenses oral semaglutide or oral tirzepatide depending on what the clinician decides. ### Is Rx.com the same company as RxPros? No. Rx.com's own FAQ states that Rx.com and RxPros are separate, unaffiliated companies. Rx.com has no access to RxPros accounts, orders or refunds. ### Are the GLP-1 medications at telos rx and Rx.com FDA-approved? No. The compounded semaglutide and compounded tirzepatide offered by both services are not FDA-approved. Both companies state this on their own pages. A licensed provider decides whether a compounded option suits your history. ### Can I switch from Rx.com to telos rx? Yes. You can start a new online visit with telos rx at any time. Share your full health history, including your current medication and current dose. Any prescription is subject to medical approval by a licensed provider. _telos rx is LegitScript-certified. Compounded medication is not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and individual results vary. telos rx operates as an online-first, asynchronous telehealth service. Pricing and program details for Rx.com were taken from its public website and are accurate as of publication._ Start your private evaluation at [telos rx](https://telosrx.com). --- > Source: [Telos RX](https://www.telosrx.com/blogs/glp1/telosrx-vs-rx-com)