NAD+ dosing is set by a licensed provider through TelosRX, not by a fixed number printed on a box. The basics are straightforward even so: a starting schedule, a period of watching how you respond, and adjustments made by your provider rather than by trial and error on your own.
There is no universal NAD+ dose that fits everyone. That is why TelosRX pairs the nasal spray with an actual provider review rather than a one-size label on a box. Your provider sets a starting frequency based on your intake, checks in as you continue, and adjusts from there over time. Guessing at your own schedule on your own is the one thing worth avoiding entirely.
Start your intake →Why NAD+ dosing is individualized rather than fixed
Unlike a drug with decades of large trials behind it, NAD+ nasal spray is a compounded medication with a much thinner published evidence base. That gap is exactly why a provider sets your schedule individually instead of applying one number to every patient.
Your starting point depends on your health history, any other peptides or medications you take, and what your provider learns during intake. Two people can end up with different starting schedules for reasons that have nothing to do with one being "healthier" than the other.
This is a compounded medication, not FDA-approved, and it is prepared by partner compounding pharmacies in the United States. Every dosing decision made for you is subject to medical approval by a licensed provider, start to finish.
What a typical starting period looks like
Most new patients begin at a conservative frequency while their provider observes how they tolerate it. This is a common approach across compounded peptides generally, not something specific to being cautious with you individually.
Your provider may ask you to check in after the first couple of weeks, either through a scheduled follow-up or simply by messaging your care team with how things are going. That feedback shapes whether your schedule stays the same or changes.
Do not expect a rigid timeline that applies to everyone. Some patients stay on their starting schedule for months. Others have it adjusted sooner. Your provider is responding to your situation, not following a universal script.
Why you will not find a specific number here
This article intentionally does not list specific dosing amounts or a reconstitution ratio, and that is not an oversight. Specific dosing depends on your individual plan, and printing a generic number would encourage people to use it instead of the one their own provider actually sets.
If you want to know your specific dose, the answer is always the same: ask your provider. That is not a deflection. It reflects that the number that matters is the one written for you, not a general figure that applies loosely to a population.
Key takeaway: The right NAD+ dose is the one your provider sets for you, reviewed and adjusted over time. There is no shortcut number worth substituting for that process, no matter how confidently it is presented elsewhere.
How adjustments get made over time
TelosRX plans include dose adjustments as a standard part of ongoing care, not an extra you request separately. If your provider thinks a change makes sense based on how you are doing, they will raise it with you rather than leaving you to guess.
Quarterly labs are also part of the plan. Bloodwork gives your provider objective information to weigh alongside how you say you feel, which produces a more grounded adjustment than subjective reporting alone.
Unlimited care-team messaging means you do not have to wait for a quarterly check-in if something changes sooner. Message your care team anytime a question about your schedule comes up.
Common mistakes people make with dosing on their own
Increasing frequency because a first few uses did not produce a noticeable feeling is a common misstep. Early research into NAD+ and cellular energy pathways does not support the idea that more, sooner, is automatically better or safer.
Copying a schedule from a friend, a supplement forum, or a video is another common error. Those sources are not weighing your health history, your other medications, or your provider's specific plan for you.
Skipping your check-ins because things feel fine is a quieter mistake. A stable feeling is exactly the information your provider wants to confirm your current schedule is working, not a reason to stop reporting in.
How dosing questions fit into the bigger picture
Some patients using NAD+ nasal spray are also managing a plan for another compounded peptide, such as BPC-157 or sermorelin. Dosing decisions for each are made independently, even when a provider is coordinating your overall plan.
If you are combining approaches, tell your provider about everything you are using, not just NAD+ nasal spray. A full picture is what allows an appropriate schedule for each element of your plan rather than a set of guesses stacked on top of each other.
For general background on how NAD+ functions in cellular metabolism, see the NIH overview of NAD+ in cellular and metabolic signaling. For how compounded medication like this is regulated in the United States, see the FDA overview of drug compounding.
Keeping a simple log worth bringing to your check-in
A short note after each use gives your provider more to work with than a vague memory at your next check-in. Record the date, roughly how you felt afterward, and anything unusual.
You do not need a formal spreadsheet. A note on your phone is enough, and it removes the guesswork of trying to recall three weeks of sessions from memory when your provider asks how things have been going.
This habit becomes especially useful if your provider ever adjusts your schedule, since you will have a clear before-and-after record to compare rather than a general impression that things feel different somehow.
What to do if your current schedule does not feel right
Message your care team rather than adjusting on your own, even a small change. A schedule that feels slightly off is worth a real conversation, since a provider may see a reason behind it that is not obvious from where you are sitting.
Not on a plan yet and wondering where you would start? Start your intake with TelosRX and a provider will walk you through what a starting schedule for your situation would look like.
What your provider actually reviews before setting a schedule
Your intake covers more ground than a quick form suggests. Your provider looks at your general health history, current medications and supplements, and any relevant past reactions before landing on a starting point for your schedule.
Body size, general activity level, and how you describe your goals also factor in, though not in a mechanical formula sense. A provider is weighing your answers as a whole picture rather than running numbers through a calculator.
If any part of your history changes between your intake and a later check-in, mention it. A provider making a schedule decision works from the most current information you give them, not from what you reported months earlier.
How this compares with dosing for other compounded peptides
Providers take a similarly individualized approach across the compounded peptides TelosRX offers, not just NAD+ nasal spray. The underlying reasoning is consistent: a thinner evidence base calls for closer oversight than a long-established prescription drug requires.
That said, each peptide is reviewed on its own terms. A schedule decision for NAD+ nasal spray does not automatically apply to a different compound, even if you are using more than one at the same time.
If you are new to compounded peptides generally, expect the same pattern wherever you start. An individualized plan, a period of observation, and adjustments from a provider replace any fixed number handed to everyone.
Patience during the early weeks
It is tempting to judge a schedule too early, especially if you were expecting to feel something dramatic right away. Early research into NAD+ does not support expecting a fast, obvious signal, and a provider is not withholding information by saying so.
Give your provider's chosen timeline a real chance before deciding anything needs to change. Reporting how you feel at your check-in gives them useful information regardless of whether that feeling is dramatic, subtle, or unclear.
If weeks pass and you genuinely have questions about whether your schedule is right for you, that is exactly what a check-in or a message to your care team is for. Uncertainty is a normal part of starting something new, not a sign that something has gone wrong.
Frequently Asked Questions
Is there a standard NAD+ nasal spray dose?
No single dose applies to everyone. TelosRX providers set an individual starting schedule based on your intake, then adjust it over time as part of your ongoing plan. There is no generic number that replaces that review.
Why won't this article list a specific dose?
Because the dose that matters is the one your own provider sets for you, not a generic figure. Publishing a specific number would encourage people to use it instead of the individualized schedule their provider actually prescribes.
How often will my dosing be reviewed?
TelosRX plans include quarterly labs and ongoing dose adjustments as standard, plus unlimited care-team messaging if something comes up sooner. Your provider reviews your situation on an ongoing basis rather than a single fixed schedule.
Can I increase my own frequency if I do not notice anything?
No. Adjusting frequency is subject to medical approval by a licensed provider. Message your care team if you have questions about how things are going instead of changing your routine on your own.
Does combining NAD+ with another peptide change dosing?
It can factor into your provider's overall plan, which is why disclosing everything you use matters. Each peptide is still dosed individually, and your provider coordinates the full picture rather than treating them as unrelated.
What if I want to stop using NAD+ nasal spray?
Message your care team before you stop. Any change to your plan, including stopping altogether, is subject to medical approval by a licensed provider, and your provider can advise on the best way to do it.
TelosRX is LegitScript-certified. NAD+ nasal spray is a compounded medication and is not FDA-approved. It is prepared by partner compounding pharmacies in the United States. This article is general information, not medical advice, and does not replace guidance from your own provider. Use of NAD+ nasal spray is subject to medical approval by a licensed provider, and approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
Questions about NAD+ nasal spray? Message the TelosRX care team or start your evaluation at TelosRX.