Comparing TelosRX and AvataCore looks simple at first glance, because both advertise $99. The difference is what happens in month two. At TelosRX, $99 a month for semaglutide is the ongoing rate. At AvataCore, $99 covers the first 4-week cycle, after which its own terms state the plan renews at $299 for semaglutide and $299 to $399 for tirzepatide. Both are LegitScript-certified and both offer a needle-free oral route.
Both platforms will start you at $99. Only one of them keeps you there. If you intend to stay on a GLP-1 for longer than a month, TelosRX costs materially less. AvataCore is worth considering if you want a short trial of an oral GLP-1, or value its included dietician visits and coaching.
Start your intake →Quick comparison: TelosRX vs AvataCore
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed. Individual results vary.
What is TelosRX?
TelosRX is an online-first, LegitScript-certified telehealth service focused on GLP-1 weight management.
The process is asynchronous. You complete a short intake online, and a US-licensed provider reviews it, typically within hours. There is no appointment to schedule.
Medications are compounded by licensed US pharmacies and shipped free within 48 hours if approved. Unlimited messaging with your care team, provider-managed dose adjustments and quarterly labs are included at no extra cost. Your monthly price does not change as your dose is titrated.
Compare all four GLP-1 options side by side, or start your treatment.
What is AvataCore?
AvataCore is a LegitScript-certified telehealth service whose headline offer is an oral GLP-1, positioned squarely at people who do not want injections. That is a real and underserved preference, and building a whole programme around it is a sensible bet.
It has a two-minute qualification quiz with no card required, free 1 to 2 day shipping, no membership fee, HSA and FSA eligibility, and a published phone line. It also includes dietician visits and care coaching in the plan, which is more hands-on nutrition support than most GLP-1 services bundle in, and worth real money if you would use it.
AvataCore also lists brand-name products such as Wegovy and Zepbound. Read that section carefully: its own disclaimer states these are shown for reference only and are not sold, dispensed or shipped by AvataCore. If prescribed, you fill them at your own pharmacy at your own cost.
The $99 question
Both services put $99 in the headline, so it is worth being precise about what each one means by it.
At TelosRX, $99 a month is the ongoing rate for injectable semaglutide. It does not step up after a introductory period, and it does not change as your dose is titrated.
At AvataCore, $99 is a first-cycle rate. Its own subscription terms state it plainly: the reserved rate applies to your first 4-week cycle, after which, unless you cancel, the plan renews every 4 weeks at the standard rate of $299 for semaglutide plans and $299 to $399 for tirzepatide plans, depending on the plan selected at checkout.
To AvataCore's credit, that is disclosed on the same page rather than hidden, and the exact renewal amount is shown at checkout before you pay. But the number in the headline, the page title and the scrolling banner is $99, and the number most patients will actually pay from cycle two onward is $299.
There is a second detail worth catching. AvataCore bills every 4 weeks, not monthly. There are 13 four-week cycles in a year, not 12. So a plan quoted "per month" at $299 is 13 payments of $299 across a year, not 12.
Key takeaway: Run the arithmetic on a full year at each service's own published rates. AvataCore semaglutide is $99 for the first cycle plus twelve renewals at $299, which is $3,687. TelosRX semaglutide at its as-low-as rate across twelve months is $1,188. The first month looks identical. The year does not.
Medications: what each platform offers
Both platforms work with the same drug class. Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GLP-1 and GIP agonist. These ingredients form the basis of FDA-approved brands and are widely studied for weight management. For background, see the NIH NIDDK overview and the FDA announcement on tirzepatide for weight management.
AvataCore offers compounded semaglutide in both oral and injectable form, and compounded tirzepatide. Its oral route is the centrepiece of the offer rather than a secondary option, which is a genuine point of difference from most competitors.
TelosRX offers injectable semaglutide and injectable tirzepatide, plus needle-free oral tirzepatide and a microdosed tirzepatide protocol for people who want to ease in at a lower dose. Compounded medications from either platform are not FDA-approved and have not been evaluated by the FDA for safety, efficacy or quality.
Weight-loss projections: what the numbers are based on
AvataCore's landing page includes a projection tool that estimates how much weight you might lose over a chosen timeline, and states that it is based on published clinical trial data for GLP-1 medications.
That basis matters. The large published trials were run on FDA-approved branded products, not on compounded preparations. Compounded medications have not been evaluated by the FDA for safety, efficacy or quality, so trial results do not transfer to them as a promise. A projection built that way is best read as an illustration of what the molecule has done in a controlled study population, not a forecast of your result.
The same caution applies to any headline about losing a set amount every week, and to testimonials generally. AvataCore does disclose that its testimonials reflect individual experiences, that results vary and are not guaranteed, and that compensation may have been provided. That disclosure is more than many competitors offer.
TelosRX does not publish weight-loss projections, because we cannot honestly promise a number for a compounded medication.
How the process works
TelosRX is a guided, fully asynchronous program. The intake takes about five minutes. A US-licensed provider reviews it without an appointment, typically within hours, and approved medication ships with free 48-hour delivery. If you are not approved, you pay nothing.
AvataCore starts with a two-minute quiz that does not ask for a card, followed by provider review and shipping in 1 to 2 days. Its terms note that you may be required to complete additional evaluations or labs before a provider can prescribe, and that not all medications are available in every state.
Neither platform prescribes automatically. Any medication is subject to medical approval by a licensed provider. Begin your TelosRX intake to see if you qualify.
Safety and medical oversight
Both platforms are LegitScript-certified, work with US-licensed clinicians, and dispense compounded medication through licensed pharmacies. Both require provider review before any prescription is issued. AvataCore also states it is HIPAA-compliant and publishes a support phone line.
GLP-1 medications are not right for everyone. Providers screen for issues including a personal or family history of medullary thyroid cancer, pancreatitis and pregnancy. Side effects are most often digestive, especially early on, and typically ease with gradual dose titration.
Share your full medical history during intake on either platform, since approval is subject to medical review and is not guaranteed.
Which service is right for you?
Best if you plan to stay on treatment beyond the first month and want a price that does not step up, plus needle-free oral tirzepatide, a microdosed option and quarterly labs included.
Best if you want to try an oral GLP-1 for a cycle before committing, or you would genuinely use the included dietician visits and care coaching. Check the renewal rate at checkout before you start.
AvataCore is a certified service with a clear needle-free proposition and better nutrition support than most. If you expect to be on a GLP-1 for months rather than weeks, the renewal rate is the number that decides this comparison, and TelosRX is substantially lower.
Frequently Asked Questions
Is AvataCore really $99 a month?
$99 is AvataCore's first 4-week cycle rate for compounded semaglutide. Its subscription terms state that the plan then renews every 4 weeks at the standard rate of $299 for semaglutide plans and $299 to $399 for tirzepatide plans. The renewal amount is shown at checkout before you pay. At TelosRX, as low as $99 a month for semaglutide is the ongoing rate, not an introductory one.
What does a full year cost at each service?
Using each service's own published rates, AvataCore semaglutide is $99 for the first cycle plus twelve renewals at $299, totalling $3,687, because 4-week billing means 13 cycles a year. TelosRX semaglutide at its as-low-as rate across twelve months is $1,188. Your actual cost depends on the plan a provider approves.
Does AvataCore sell Wegovy or Zepbound?
No. AvataCore lists brand-name medications for reference, and its own disclaimer states they are not sold, dispensed or shipped by AvataCore. If prescribed, you fill them at your own pharmacy. TelosRX prescribes compounded medication only.
Do both offer a needle-free GLP-1?
Yes. An oral GLP-1 is the centrepiece of AvataCore's offer. TelosRX offers oral, sublingual tirzepatide as low as $129 a month, plus a microdosed tirzepatide protocol as low as $116 a month.
Are AvataCore's weight-loss projections reliable?
Its projection tool states that it is based on published clinical trial data for GLP-1 medications. Those trials were conducted on FDA-approved branded products, not compounded preparations, and compounded medications have not been evaluated by the FDA for safety, efficacy or quality. Treat any projection as an illustration rather than a forecast. Individual results vary and no service can guarantee an outcome.
Who is AvataCore best for?
AvataCore suits someone who wants to trial an oral GLP-1 for a cycle, values included dietician visits and coaching, and has read the renewal rate. If you expect to stay on treatment for several months, TelosRX is the lower ongoing cost.
TelosRX is LegitScript-certified. Compounded medications from either platform are not FDA-approved and have not been evaluated by the FDA for safety, efficacy or quality. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service. AvataCore details, including introductory and renewal pricing, billing cadence, medication list and disclosures, were taken from its own published landing page and subscription terms in August 2026 and may change.
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