Choosing between TelosRX and Enhance MD for GLP-1 weight loss comes down to what you value. TelosRX publishes every price upfront and runs a fast, fully online process. Enhance MD pairs its GLP-1 programs with lab work. Both require approval by a licensed provider.
For transparent pricing and a fast online start, TelosRX is the simpler choice. Enhance MD fits if you prefer a lab-first onboarding with a virtual provider visit before you begin.
Start your intake →Quick comparison: TelosRX vs Enhance MD
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed.
What is TelosRX?
TelosRX is an online-first, LegitScript-certified telehealth pharmacy. It focuses on GLP-1 weight management with compounded tirzepatide and semaglutide.
The service is asynchronous. You finish a short intake online, and a US-licensed provider reviews it, usually within a few hours. There is no appointment to book.
Medications are compounded by licensed US pharmacies and shipped to your door. You can message your care team anytime, and pricing is published upfront, so there are no surprises.
Browse the tirzepatide and semaglutide options, or start your treatment.
What is Enhance MD?
Enhance MD is a telehealth program focused on metabolic health and weight management. It offers compounded semaglutide, compounded tirzepatide, and a combination program, plus a microdosing tirzepatide option.
The onboarding leans on lab work. You complete a medical intake, arrange blood tests at a lab, then connect with a licensed provider through a virtual visit once results are in. Providers monitor progress and adjust as needed.
Enhance MD publishes tiered starting prices and emphasizes the same price at every dose. If you value a lab-first start with a scheduled provider visit, that structure is a genuine strength.
Medications: what each program offers
Both programs center on the same drug class. Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GLP-1 and GIP agonist.
These ingredients are studied for weight management and are the basis of FDA-approved brands like Wegovy and Zepbound. The compounded versions offered by both TelosRX and Enhance MD are not FDA-approved.
TelosRX also offers needle-free oral tirzepatide and a microdosed option. Enhance MD offers a semaglutide-plus-tirzepatide combination program. For background, see the NIH NIDDK overview and the FDA note on tirzepatide for weight management.
Key takeaway: TelosRX lists every plan price upfront, including the ongoing monthly rate. With Enhance MD, the introductory first-month price steps up to a higher recurring charge after month one.
Pricing and transparency
This is the clearest difference. TelosRX lists every plan price before you sign up, and the headline price is the price you keep.
- From $49 a month — microdosed tirzepatide, 12-month plan
- $99 your first month — standard tirzepatide, 12-month plan
- $145, $199, or $399 first month — 6-month, 3-month, or single-month plans
Enhance MD also publishes prices, but as introductory first-month rates. Its semaglutide tier starts near $49 the first month, then steps up to a higher monthly charge. The tirzepatide and combination tiers are priced above that. Both accept the kind of payment flexibility many shoppers want, and TelosRX is FSA and HSA eligible.
Start your intake to see your plan price in minutes.
How the process works
TelosRX is built for speed. The intake takes about five minutes. A licensed provider reviews it asynchronously, often within hours, and approved medication ships with free 48-hour delivery.
Enhance MD adds more steps before you begin. You finish an intake, complete blood work at a lab, then attend a virtual visit with a provider once results return. It is a more structured, lab-first path by design.
Neither prescribes automatically. Any medication is subject to medical approval by a licensed provider. You can start your intake online in minutes.
Coaching and ongoing support
Enhance MD leans into structured monitoring. It pairs your program with provider oversight, periodic metabolic labs, and ongoing support as your dose changes.
TelosRX keeps support focused and direct. You get unlimited messaging with your care team, dose adjustments as your body changes, and quarterly labs.
One is not strictly better. Enhance MD suits people who want a lab-anchored, provider-led cadence. TelosRX suits people who want responsive medical support without extra onboarding steps.
Safety and medical oversight
Both programs gate medication behind a licensed provider. No one is prescribed automatically.
GLP-1 medications are not for everyone. Providers screen for issues like a personal or family history of medullary thyroid cancer, pancreatitis, and pregnancy. Side effects can include nausea and digestive changes, especially early on.
TelosRX includes quarterly labs and care-team messaging, so concerns get flagged. Share your full history during intake, since approval is subject to medical review.
Which service is right for you?
Best for transparent pricing, a fast async start, and a streamlined, medication-first program from a LegitScript-certified pharmacy.
Best for a lab-first onboarding with a virtual provider visit and structured, provider-led monitoring.
For most people who want clear costs and a simple online start, TelosRX is the more straightforward choice.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is a LegitScript-certified telehealth pharmacy. Medications are compounded by licensed US pharmacies, and every prescription is subject to medical approval by a licensed provider. Pricing is published upfront, and you can cancel anytime. The model is online-first and asynchronous, so there is no appointment to book.
Are the GLP-1 medications FDA-approved?
The compounded tirzepatide and semaglutide offered by both TelosRX and Enhance MD are not FDA-approved. They are prepared under federal compounding regulations by licensed US pharmacies. The same active ingredients underpin FDA-approved brands like Wegovy and Zepbound, but compounded formulations are distinct and are not reviewed by the FDA.
How much does TelosRX cost compared to Enhance MD?
TelosRX publishes its pricing, and the headline price is what you keep. GLP-1 plans start from $49 a month (microdosed tirzepatide, 12-month plan), with standard tirzepatide from $99 your first month. Enhance MD publishes introductory first-month prices that step up to higher recurring monthly charges after the first month.
Is TelosRX fully online?
Yes. TelosRX is online-first and asynchronous. You finish a short intake, a licensed provider reviews it, and approved medication ships to you with free 48-hour delivery. No appointment is required. Enhance MD, by contrast, asks you to complete lab work and attend a virtual visit before you begin.
Can I switch from Enhance MD to TelosRX?
Many people compare programs before deciding. You can start a new TelosRX intake at any time. A licensed provider reviews your history and goals before any medication is approved. Share details about your current or past program during intake, since approval is subject to medical review and is not guaranteed.
How fast is provider review at TelosRX?
Intake review is asynchronous and usually happens within a few hours. If approved, medication ships with free 48-hour delivery. Timing can vary by individual case and by the information you provide. Enhance MD typically takes longer to start, because it asks for lab results and a scheduled virtual visit first.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
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