Choosing between TelosRX and Fifty410 for GLP-1 weight loss comes down to what you value. TelosRX offers transparent, published pricing and a fast, fully online async process. Fifty410 pairs compounded GLP-1 options with a mobile app and provider support. Both require approval by a licensed provider.
TelosRX is the simpler, more transparent choice. Prices start from $49 a month and a provider reviews your intake asynchronously, often within hours. Fifty410 fits if you want app-based tools and a multi-category service alongside your GLP-1 plan.
Start your intake →Quick comparison: TelosRX vs Fifty410
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed.
What is TelosRX?
TelosRX is an online-first, asynchronous telehealth pharmacy for weight management. You complete a short intake online. A US-licensed provider reviews it without a scheduled appointment, often within hours.
The program focuses on compounded GLP-1 medications. These include compounded tirzepatide and compounded semaglutide, prepared by licensed US pharmacies. Compounded medications are not FDA-approved.
Pricing is published upfront, so you see plan costs before you sign up. There is no quiz wall between you and the price. TelosRX is LegitScript-certified, and your plan includes free 48-hour shipping if approved, unlimited care-team messaging, quarterly labs, and dose adjustments. You can cancel anytime.
You can read more about tirzepatide and semaglutide on the product pages. Ready to begin? Start your treatment with a quick online visit.
What is Fifty410?
Fifty410 is a telehealth service that offers compounded GLP-1 medications for weight loss. It also covers other categories, including hair growth and longevity options. Weight loss is its primary focus.
The model is fully online. You complete a short health questionnaire, and a licensed provider reviews it within 24 to 48 hours. Fifty410 adds a mobile app, a patient portal, secure messaging, and community access.
Fifty410 ships compounded semaglutide and tirzepatide free, typically in one to two days. It accepts FSA and HSA cards, plus Afterpay and Affirm for flexible payment. Its app-based tools and multi-category menu are genuine strengths if you want more than a single GLP-1 plan. The dosage calculator and progress tracking can help some people stay consistent.
Medications: what each program offers
Semaglutide is a GLP-1 medication. Tirzepatide works on two receptors, GLP-1 and GIP. Both are prescribed for weight management when a provider approves them.
Both TelosRX and Fifty410 offer compounded versions of these medications. Compounded versions are not FDA-approved. TelosRX also offers needle-free oral tirzepatide and a microdosed option.
For background on how these medications are used, see the NIH NIDDK overview and this FDA announcement. Your provider decides what is appropriate for you.
Key takeaway: TelosRX publishes every plan price upfront, starting from $49 a month. With Fifty410, the detailed tiers live on separate pricing pages.
Pricing and transparency
TelosRX lists plan prices before you commit. Here is how the main GLP-1 plans are structured.
- From $49/mo for microdosed tirzepatide on the 12-month plan.
- $99 for the first month of standard tirzepatide on the 12-month plan.
- $145, $199, or $399 for the first month on the 6-month, 3-month, or single-month plans.
Fifty410 shows a "starting at" figure on its weight-loss page, with semaglutide from about $99 a month and detailed tiers on separate pricing pages. Both services accept FSA and HSA. Start your intake to see your plan price in minutes.
How the process works
With TelosRX, you complete a roughly 5-minute online intake. You answer questions about your health history, current medications, and goals. A US-licensed provider reviews it asynchronously, often within hours, with no appointment. If approved, your medication ships with free 48-hour delivery. You can message the care team anytime with questions.
Fifty410 follows a similar online path. You complete an assessment, a provider reviews it within 24 to 48 hours, and approved medication ships free in one to two days. You then track progress through the app. Any medication is subject to medical approval by a licensed provider.
The main difference is speed and simplicity. TelosRX keeps the whole flow asynchronous, so you never wait for a scheduled slot. Start your online visit and see what a provider recommends.
Coaching and ongoing support
Fifty410 leans on app-based tools, a patient portal, a dosage calculator, and community access. If you like structured digital touchpoints and progress tracking, that is a real benefit.
TelosRX keeps support simple and direct. You get unlimited care-team messaging, dose adjustments, and quarterly labs. There is no app to learn and no cadence to keep up with. You reach out when you need something, and the care team responds. Both approaches work. It comes down to whether you prefer an app-driven experience or a streamlined, medication-first program.
Safety and medical oversight
Both services are provider-gated. A licensed provider reviews your history before any prescription. GLP-1 medications are not right for everyone.
Providers screen for a personal or family history of medullary thyroid cancer, a history of pancreatitis, and pregnancy. Common side effects include nausea and other digestive symptoms, which often ease as your body adjusts. Share your full health history so your provider can make a safe call. TelosRX includes quarterly labs to support ongoing oversight. Approval is subject to medical review and is not guaranteed.
Which service is right for you?
Best for transparent pricing, a fast async start, and a streamlined, medication-first program from a LegitScript-certified pharmacy.
Best for people who want app-based tracking tools, community access, and a multi-category telehealth service alongside their GLP-1 plan.
For most people who want clear pricing and a fast online start, TelosRX is the more straightforward choice. If app-based tools matter most to you, Fifty410 is worth a look.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is a LegitScript-certified, online-first telehealth pharmacy. Every plan is reviewed by a US-licensed provider before any medication is dispensed. Medications are compounded by licensed US pharmacies. Pricing is published upfront, so you can see plan costs before you sign up. Approval is subject to medical review and is not guaranteed.
Are the GLP-1 medications FDA-approved?
No. The compounded medications offered by both TelosRX and Fifty410 are not FDA-approved. They are prepared by licensed US pharmacies under federal compounding regulations. Brand-name products are a separate category. A licensed provider decides whether a compounded GLP-1 medication is appropriate for you based on your health history.
How much does TelosRX cost compared to Fifty410?
TelosRX plans start from $49 a month for microdosed tirzepatide on the 12-month plan. Standard tirzepatide is $99 for the first month on the 12-month plan. Fifty410 lists semaglutide from about $99 a month, with detailed tiers on separate pricing pages. TelosRX publishes every plan price upfront.
Is TelosRX fully online?
Yes. TelosRX is online-first and asynchronous. You complete a roughly 5-minute intake online, and a US-licensed provider reviews it without a scheduled appointment, often within hours. If approved, your medication ships with free 48-hour delivery. There are no office visits and no phone appointments required to begin.
Can I switch from Fifty410 to TelosRX?
Yes. You can start a new online visit with TelosRX at any time. Complete the short intake and share your full health history, including any current medications and your current dose. A licensed provider reviews your information and decides what is appropriate. Approval is subject to medical review and is not guaranteed.
How fast is provider review at TelosRX?
Provider review is asynchronous, so you do not wait for an appointment. A US-licensed provider often reviews your intake within hours. If approved, your medication ships with free 48-hour delivery. Timing can vary based on your responses and any follow-up questions the provider may need to ask before approval.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
Start your private evaluation at TelosRX.