TelosRX and MangoRx both offer compounded GLP-1 medications through telehealth, but the medication format itself is a real point of difference: TelosRX prescribes injectable compounded tirzepatide and semaglutide (plus oral and microdosed tirzepatide options), while MangoRx, a brand of publicly traded Mangoceuticals, Inc. (Nasdaq: MGRX), sells its GLP-1s exclusively as oral dissolvable tablets under the names SLIM and TRIM.
TelosRX starts at $99/month for compounded semaglutide, with published pricing across every tier and fast, asynchronous provider review. MangoRx's oral tablets run higher — TRIM (tirzepatide) at roughly $399/month and SLIM (semaglutide) at roughly $299–399/month, depending on the source. If you're comparing on price and transparency, TelosRX is the lower-cost, fully disclosed option; if you specifically want to avoid injections, MangoRx's tablet format is the differentiator worth weighing.
Start your intake →Quick comparison: TelosRX vs MangoRx
Note: Compounded tirzepatide and compounded semaglutide, whether injectable or in oral tablet form, are not FDA-approved medications. They are prepared by licensed pharmacies under federal and state compounding regulations. This comparison covers compounded GLP-1 telehealth programs, not the branded, patented injectable medications themselves.
What is TelosRX?
TelosRX is an online-first, asynchronous telehealth practice built specifically around compounded GLP-1 weight-management medications. Instead of booking a video call and waiting for an open slot, patients complete a short intake questionnaire online — typically in about five minutes — covering medical history, current medications, and weight-loss goals. A licensed provider reviews that intake and, if appropriate, issues an approval and prescription, often within hours rather than days. There's no mandatory video visit and no waiting room; the front door of the process happens on your schedule.
Once approved, patients can choose compounded tirzepatide or compounded semaglutide, the two active ingredients behind the FDA-approved brand-name GLP-1/GIP medications. TelosRX's versions are injectable and are prepared by licensed compounding pharmacies under federal compounding regulations rather than manufactured by the original branded drugmakers, which is part of what allows TelosRX to offer them at a lower cash price. Dosing is titrated by a provider based on how each patient responds and tolerates the medication, and prescriptions ship directly to the patient's door.
TelosRX is LegitScript-certified, a distinction that verifies the pharmacy network and prescribing practices meet recognized standards for online pharmacies. Plans are cash-pay but FSA/HSA-eligible, and pricing is published in full on the website rather than disclosed only after a lead form — including compounded semaglutide starting at $99/month, microdosed tirzepatide starting at $116/month, and standard tirzepatide starting at $139/month. Patients who are hesitant about self-injecting can also review oral tirzepatide and microdosed tirzepatide options. Start your online visit to see which plan and dose a provider recommends for you.
What is MangoRx?
MangoRx (mangorx.com) is a brand of Mangoceuticals, Inc., a company publicly traded on the Nasdaq under the ticker MGRX. MangoRx built its business on a men's health product line and later added compounded GLP-1 medications to that lineup, branded internally as SLIM (compounded semaglutide) and TRIM (compounded tirzepatide).
The defining feature of MangoRx's GLP-1 offering is the delivery format: both SLIM and TRIM are dispensed as oral dissolvable tablets rather than injectable pens or vials. Patients access the medications through a telemedicine intake process rather than an in-person visit.
On pricing, MangoRx's TRIM (tirzepatide) runs at approximately $399/month, and SLIM (semaglutide) at approximately $299–399/month — figures that vary somewhat depending on the source, so treat them as approximate rather than fixed. As a publicly traded company, MangoRx's parent, Mangoceuticals, Inc., also publishes financial disclosures that aren't typical of privately held telehealth competitors.
Medications: what each program offers
Both TelosRX and MangoRx work with the same two active ingredients — semaglutide and tirzepatide — which belong to the GLP-1 receptor agonist class (tirzepatide also acts on the GIP receptor). This class of medication works by slowing digestion, increasing feelings of fullness, and helping regulate appetite and blood sugar. The FDA has approved brand-name versions of these ingredients for chronic weight management; you can read more from the National Institute of Diabetes and Digestive and Kidney Diseases and the FDA's announcement on chronic weight-management medications. Because both TelosRX and MangoRx dispense compounded — not brand-name — versions, individual results vary and neither program should be compared to clinical trial data generated on the patented, FDA-approved drugs.
The meaningful difference here is format, not ingredient. TelosRX delivers its medications as injectables (with oral and microdosed tirzepatide variations also available), while MangoRx delivers both of its GLP-1 products exclusively as oral dissolvable tablets. Some patients strongly prefer avoiding needles altogether, which is where MangoRx's format may appeal; others prefer the dosing precision and established track record of injectable delivery, which is where TelosRX's core product line is built.
Key takeaway: The decision between TelosRX and MangoRx often comes down to format and price as much as anything else. TelosRX offers lower published starting pricing and injectable (plus oral/microdosed tirzepatide) options with transparent tiers; MangoRx's draw is a needle-free oral tablet format at a higher, approximate monthly price point.
Pricing and transparency
TelosRX publishes its full pricing structure directly on its site:
- Compounded semaglutide from $99/month
- Microdosed tirzepatide from $116/month
- Needle-free oral tirzepatide from $129/month
- Standard tirzepatide from $139/month
MangoRx publishes approximate monthly pricing for its oral tablet plans: TRIM (tirzepatide) at roughly $399/month, and SLIM (semaglutide) at roughly $299–399/month. Because reported figures vary by source, treat these as approximate rather than fixed list prices, and confirm current pricing directly with MangoRx before enrolling.
How the process works
TelosRX's process starts with a short online intake questionnaire, reviewed asynchronously by a licensed provider, with approvals commonly issued within hours. MangoRx uses a telemedicine intake model, in which patients complete an online evaluation that is reviewed as part of a physician-led telemedicine process before a prescription for SLIM or TRIM tablets is issued.
Format and support
TelosRX's ongoing support includes unlimited messaging with the care team and quarterly labs to help track progress on an injectable regimen. MangoRx's differentiator isn't a coaching layer — it's the tablet format itself, which removes the need for self-injection and may appeal to patients who are needle-averse or who want a GLP-1 option that fits alongside an existing men's health regimen from the same company.
Safety and medical oversight
With any GLP-1 program, approval isn't automatic. A licensed provider reviews each patient's intake and medical history, screening for factors such as a personal or family history of medullary thyroid cancer, pancreatitis, and pregnancy, among other contraindications. Nausea and other gastrointestinal side effects are common, especially early in treatment or after a dose increase, regardless of whether the medication is injectable or oral. Approval is never guaranteed, and patients should disclose their full medical history so a provider can make an informed decision.
Which service is right for you?
TelosRX
Best for patients who want lower published starting pricing, injectable dosing precision (with oral/microdosed tirzepatide alternatives available), and fast asynchronous provider review.
Start your intake →MangoRx
May suit patients who specifically want to avoid injections and prefer an oral dissolvable tablet, at a higher approximate monthly price.
Want injectable or oral compounded GLP-1 pricing you can see before you commit? Start your online visit with TelosRX today.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is LegitScript-certified, meaning its pharmacy network and prescribing practices have been reviewed against recognized standards for online pharmacies.
Are the medications FDA-approved?
No. TelosRX dispenses compounded tirzepatide and compounded semaglutide, which are not FDA-approved products. They are prepared by licensed pharmacies under federal and state compounding regulations. MangoRx's SLIM and TRIM oral tablets are likewise compounded, not FDA-approved, products.
How much does TelosRX cost vs MangoRx?
TelosRX starts at $99/month for compounded semaglutide, with microdosed tirzepatide from $116/month and standard tirzepatide from $139/month. MangoRx's TRIM (tirzepatide) tablets run at approximately $399/month, and SLIM (semaglutide) tablets at approximately $299–399/month.
Is TelosRX fully online?
Yes. TelosRX operates as an asynchronous, online-first telehealth service — intake, provider review, and prescription happen without a mandatory video visit.
Can I switch from MangoRx to TelosRX?
Yes. You can complete TelosRX's online intake and share your current medication history, including any prior SLIM or TRIM use, for provider review.
How fast is provider review?
TelosRX intake is typically reviewed by a licensed provider within hours. MangoRx's telemedicine review timing is not published in detail.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service. Ready to get started? Visit TelosRX to begin your intake today.