Comparing TelosRX and Native Med for GLP-1 weight loss comes down to price, care model, and medication flexibility. TelosRX starts significantly lower and adds needle-free options with fully asynchronous intake. Native Med includes a telehealth call and also serves its members. Both are LegitScript-certified.
For the lowest entry price, needle-free options, and a fully asynchronous experience, TelosRX is a compelling choice. Native Med suits those who prefer a telehealth call with a provider as part of their intake and are comfortable with a higher starting price.
Start your intake →Quick comparison: TelosRX vs Native Med
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed.
What is TelosRX?
TelosRX is an online-first, LegitScript-certified telehealth pharmacy specializing in GLP-1 weight management. The service is built entirely around asynchronous care — you complete a short intake online, and a licensed US provider reviews it, typically within hours. There is no appointment to book and no call to schedule.
Medications are compounded by licensed US compounding pharmacies and shipped directly to your door with free 48-hour delivery if you are approved. You can message your care team at any time, receive dose adjustments as needed, and access quarterly labs. All pricing is published upfront with no hidden fees.
TelosRX offers compounded tirzepatide and compounded semaglutide as weekly injections, along with two needle-free alternatives: oral tirzepatide and microdosed tirzepatide — options not commonly found at other telehealth pharmacies. HSA and FSA payments are accepted.
What is Native Med?
Native Med is a LegitScript-certified telehealth weight-loss provider that offers compounded GLP-1 medications. Their process includes three steps: an online medical form, a telehealth call with a provider, and medication delivery. The telehealth call distinguishes their model, giving patients direct real-time contact with a provider during intake.
Native Med offers compounded semaglutide and compounded tirzepatide, with brand-name alternatives (Wegovy, Ozempic, Zepbound, Mounjaro) available at retail cost. They emphasize no membership fees, free discreet shipping, and promote 1:1 provider care. Native Med has been operating for over three years and holds a strong Trustpilot rating.
Medications: what each program offers
Both programs center on the same drug class. Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GLP-1 and GIP agonist. The compounded versions offered by both TelosRX and Native Med are not FDA-approved and are prepared under federal compounding regulations by licensed US compounding pharmacies.
These ingredients are the basis of FDA-approved brands like Wegovy and Zepbound. For an overview of prescription weight-management options, see the NIH NIDDK guide on prescription medications for obesity and the FDA announcement on tirzepatide for chronic weight management.
Where the two programs differ is in format. TelosRX adds needle-free alternatives through its oral tirzepatide and microdosed tirzepatide options, which are not widely offered elsewhere. Native Med sticks to the standard injectable compounded formats but adds the option to access brand-name medications at retail price for those who prefer FDA-approved branded drugs.
Key takeaway: Both programs are LegitScript-certified and offer compounded semaglutide and tirzepatide. TelosRX starts at $49/mo and offers needle-free formats; Native Med includes a live telehealth call and starts at $149/mo for semaglutide. Neither compounded program uses FDA-approved medications.
Pricing and transparency
Both companies publish their pricing, which is a meaningful sign of transparency in this market.
TelosRX lists every plan upfront:
- From $49 a month — microdosed tirzepatide, 12-month plan
- $99 your first month — standard tirzepatide, 12-month plan
- $145, $199, or $399 first month — 6-month, 3-month, or single-month plans
Native Med publishes starting prices as well:
- From $149 a month — compounded semaglutide
- From $259 a month — compounded tirzepatide
Native Med notes pricing may vary based on dose and program duration. Brand-name options are available at retail cost (not covered by the program pricing above). Both programs accept HSA and FSA payments and neither charges a membership fee. Start your TelosRX intake to see your personalized plan price in minutes.
How the process works
TelosRX is fully asynchronous. You complete a short online intake — typically around five minutes — and a licensed US provider reviews it, often within hours. No appointment is needed at any stage. If approved, medication ships with free 48-hour delivery directly from a licensed compounding pharmacy.
Native Med follows a three-step process: online medical form, a telehealth call with a licensed provider, and then medication delivery. The included call means patients speak directly with a provider before a prescription is issued. This adds a real-time consultation step that some patients find reassuring. Shipping is free and discreet, with delivery in approximately two to three days.
Both programs require medical approval by a licensed provider before any medication is prescribed. Neither prescribes automatically.
Coaching and ongoing support
TelosRX includes ongoing clinical support as part of the program: unlimited care-team messaging, dose adjustments as your treatment progresses, and quarterly labs to monitor your health. This structured touchpoint model means you have access to clinical guidance throughout your time on the program, not just at intake.
Native Med emphasizes 1:1 provider care and a community support element, allowing members to connect with others on the program. The live telehealth call during intake provides a real-time touchpoint that TelosRX's asynchronous model does not include. Ongoing support details beyond the initial call are not publicly detailed.
The right fit depends on your preference: TelosRX offers responsive asynchronous clinical check-ins with documented quarterly labs; Native Med offers a live provider call upfront and a community connection layer.
Safety and medical oversight
Both programs require a licensed provider to evaluate and approve each patient before any medication is issued. No one is prescribed automatically based solely on an online form.
GLP-1 medications are not appropriate for everyone. Providers screen for conditions such as a personal or family history of medullary thyroid cancer, pancreatitis, or pregnancy, among others. Common early side effects include nausea and digestive changes. As with any prescription medication, ongoing monitoring is important.
TelosRX includes quarterly labs and ongoing care-team messaging, so clinical concerns can be flagged and addressed between intake and throughout treatment. Any prescription is subject to medical approval by a licensed provider.
Which service is right for you?
Best for the lowest entry price, needle-free and microdosed options, and ongoing asynchronous clinical support from a LegitScript-certified telehealth pharmacy. No appointment needed, no hidden fees.
Best if you value a live telehealth call with a provider during your intake process, prefer speaking with someone in real time before starting, or want access to brand-name options at retail cost.
For most people looking for a low-cost, flexible start with documented ongoing support, TelosRX is the more straightforward option. If a real-time provider conversation during intake is important to you, Native Med is worth considering.
Frequently Asked Questions
Is TelosRX or Native Med a better value?
TelosRX starts at $49 a month (microdosed tirzepatide, 12-month plan) and $99 your first month for standard tirzepatide. Native Med starts at $149 a month for compounded semaglutide and $259 a month for compounded tirzepatide. Both are LegitScript-certified and charge no membership fees, but TelosRX's entry price is significantly lower. Subject to medical approval by a licensed provider.
Does Native Med require a video or phone call?
Yes. Native Med's stated process includes a telehealth call with a licensed provider as part of the three-step intake. TelosRX is fully asynchronous — you complete an online intake form, a licensed provider reviews it (often within hours), and no call or appointment is required at any stage.
Are the GLP-1 medications from TelosRX and Native Med FDA-approved?
No. Both TelosRX and Native Med offer compounded semaglutide and tirzepatide, which are not FDA-approved. They are prepared under federal compounding regulations by licensed US compounding pharmacies. Native Med also lists brand-name options (Wegovy, Zepbound, Ozempic, Mounjaro) at retail cost — those brand medications are FDA-approved.
How quickly does TelosRX ship medication?
If your intake is approved by a licensed provider, TelosRX ships with free 48-hour delivery. Native Med advertises free discreet shipping with delivery in approximately two to three days. Shipping in both cases depends on provider approval; no medication is shipped without a licensed provider's review.
Does TelosRX offer needle-free GLP-1 options?
Yes. TelosRX offers oral tirzepatide (dissolved under the tongue) and microdosed tirzepatide, both needle-free formats. These are not common across GLP-1 telehealth platforms. Native Med's publicly listed compounded options are standard injectable medications. All options are subject to medical approval by a licensed provider.
Is TelosRX legitimate and certified?
Yes. TelosRX is LegitScript-certified, which is a recognized pharmacy certification standard. Medications are compounded by licensed US compounding pharmacies, and every prescription is subject to medical approval by a licensed provider. Approval is not guaranteed, and individual results vary.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
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