Choosing between TelosRX and Novi for GLP-1 weight loss comes down to what you value. TelosRX lists every price upfront and runs a fast, fully online intake reviewed by a licensed provider, often within hours. Novi pairs compounded GLP-1 medication with included coaching and a provider visit. Both require approval by a licensed provider.
TelosRX is the simpler, more transparent choice, with plans from $49/mo and an asynchronous start measured in hours. Novi fits if you want included one-on-one coaching alongside your medication.
Start your intake →Quick comparison: TelosRX vs Novi
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed.
What is TelosRX?
TelosRX is an online-first, asynchronous telehealth service for GLP-1 weight management. You complete a short intake online. A US-licensed provider reviews it on their own time, often within hours. There's no appointment to book and no waiting room.
The program centers on compounded tirzepatide and semaglutide, prepared by licensed US pharmacies. Compounded medications are not FDA-approved. Every plan is listed publicly, so you see the price before you start. TelosRX is LegitScript-certified.
You also get unlimited care-team messaging, quarterly labs, dose adjustments, and the option to cancel anytime. Shipping is free and arrives in about 48 hours once a provider approves your plan.
You can read more about tirzepatide and semaglutide on our product pages. Ready to begin? Start your treatment with a quick online intake.
What is Novi?
Novi is an online weight loss program built around compounded GLP-1 medication. It offers compounded semaglutide, its single-action option, and compounded tirzepatide, its dual-action option. Both are sourced from US pharmacies and prepared as compounded formulas.
Novi's model includes a provider visit to start. You take a short online quiz, then meet with a US-based provider to confirm your plan. From there you get unlimited access to clinicians for check-ins, dose adjustments, and side-effect questions.
Coaching is a genuine strength here. Novi includes one-on-one coaching at no extra cost, and its pricing is all-in with the medication included. Shipping is free and arrives in about two days. Novi's prescriptions are cash-pay, though insurance may reimburse branded options.
Medications: what each program offers
Both services work with the same two GLP-1 molecules. Semaglutide is a GLP-1 receptor agonist. Tirzepatide acts on two pathways, GLP-1 and GIP, which is why it's often called dual-action. Both are used for weight management under provider supervision.
The compounded versions offered by TelosRX and Novi are not FDA-approved. Compounding lets licensed pharmacies prepare a medication to a provider's specifications. TelosRX also offers needle-free oral tirzepatide and a lower-dose microdosed option.
For background on how these medications fit into weight management, see the NIH NIDDK overview and this FDA announcement on chronic weight management medication.
Key takeaway: TelosRX starts at $49/mo with every plan listed publicly, while Novi starts at $133/mo. If upfront pricing and a fast start matter most, TelosRX has the edge.
Pricing and transparency
TelosRX publishes its full pricing so you can compare before you commit. Here's how it breaks down:
- From $49/mo for microdosed tirzepatide on the 12-month plan.
- $99 first month for standard tirzepatide on the 12-month plan.
- $145, $199, or $399 first month for the 6-month, 3-month, or single-month plans.
Novi lists all-in starting rates: from $133/mo for compounded semaglutide and from $166/mo for compounded tirzepatide, with medication and coaching included. Its longer-plan rates aren't fully shown until you start the quiz. Start your intake to see TelosRX pricing for your plan.
How the process works
With TelosRX, you complete a roughly 5-minute online intake. A US-licensed provider reviews it asynchronously, often within hours. If approved, your medication ships free and arrives in about 48 hours. No appointment, no video call.
With Novi, you take a short quiz, then meet with a US-based provider to confirm your plan. After that you get ongoing clinician support and free 2-day shipping. The provider visit is part of the process at the start.
The difference is timing. TelosRX skips the scheduled visit, so you can finish at midnight and hear back the same day. Start your intake when it suits you. Any medication is subject to medical approval by a licensed provider.
Coaching and ongoing support
Novi's included one-on-one coaching is a real benefit. If you want a coach checking in on habits and accountability, Novi delivers that as part of the plan at no extra cost. It's a fair reason to choose them.
TelosRX takes a streamlined, medication-first approach. You get unlimited care-team messaging, dose adjustments, and quarterly labs. The support is there when you need it, without a separate coaching layer. Many people prefer this. They want the medication and a responsive care team, not weekly coaching calls.
Which model suits you depends on how much hands-on coaching you want. If accountability calls keep you on track, Novi's coaching helps. If you'd rather message your care team and move on, TelosRX fits better. Neither approach is wrong. They serve different people.
Safety and medical oversight
Both programs are provider-gated, and approval is subject to medical review. GLP-1 medications aren't right for everyone. Providers screen for things like a personal or family history of medullary thyroid cancer, a history of pancreatitis, and pregnancy.
Common side effects include nausea and other digestive symptoms, especially early on. TelosRX includes quarterly labs and unlimited messaging so your care team can adjust your dose. Always share your full medical history during intake. Approval is not guaranteed.
Which service is right for you?
Best for transparent pricing, a fast async start, and a streamlined, medication-first program from a LegitScript-certified pharmacy.
Best for people who want included one-on-one coaching and a provider visit alongside their compounded GLP-1 medication.
If you value seeing prices upfront and starting in hours, TelosRX is built for you. If included coaching is your priority, Novi is worth a look. Either way, a licensed provider decides what's appropriate.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is a LegitScript-certified telehealth service. It works with US-licensed providers and licensed US compounding pharmacies. You complete an online intake, and a provider reviews your information before any prescription. Approval is subject to medical review by a licensed provider, and approval is not guaranteed.
Are the GLP-1 medications FDA-approved?
The compounded medications offered by TelosRX and Novi are not FDA-approved. Compounding lets a licensed US pharmacy prepare a medication to a provider's specifications under federal compounding regulations. A licensed provider must approve any prescription, and approval is never automatic or guaranteed.
How much does TelosRX cost compared to Novi?
TelosRX plans start from $49/mo for microdosed tirzepatide on the 12-month plan, with all plans listed publicly. Novi starts from $133/mo for compounded semaglutide and from $166/mo for compounded tirzepatide. Novi's pricing is all-in with coaching included. Your final price depends on the plan and provider approval.
Is TelosRX fully online?
Yes. TelosRX is online-first and asynchronous. You finish a roughly 5-minute intake online, and a US-licensed provider reviews it on their own schedule, often within hours. There's no appointment and no video visit to book. If approved, your medication ships free and arrives in about 48 hours.
Can I switch from Novi to TelosRX?
Yes, you can start a TelosRX intake at any time. Complete the online questionnaire and share your full medical history, including your current medication and dose. A licensed provider reviews everything and decides what's appropriate for you. Approval is subject to medical review and is not guaranteed.
How fast is provider review at TelosRX?
Because TelosRX is asynchronous, a US-licensed provider often reviews your intake within hours rather than days. You don't wait for an appointment. If the provider approves your plan, your medication ships free with delivery in about 48 hours. Review times can vary with your information and provider availability.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
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