Comparing TelosRX and Pomegranate for GLP-1 weight loss comes down to how you want to start. TelosRX is fully asynchronous: a short online intake, no appointment, and nothing owed if you are not approved. Pomegranate asks first-time GLP-1 patients to book a live telehealth consultation and pay a $75 intake fee up front. TelosRX also starts lower, at $99 a month against $119.
If you want to skip the appointment and pay nothing unless you are approved, TelosRX is the simpler and cheaper route. Pomegranate is worth considering if you actively want to speak with a provider first, like choosing your own pharmacy, or want non-GLP-1 options such as Contrave alongside.
Start your intake →Quick comparison: TelosRX vs Pomegranate
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed. Individual results vary.
What is TelosRX?
TelosRX is an online-first, LegitScript-certified telehealth service focused on GLP-1 weight management.
The process is asynchronous. You complete a short intake online, and a US-licensed provider reviews it, typically within hours. There is no appointment to schedule.
Medications are compounded by licensed US pharmacies and shipped free within 48 hours if approved. Unlimited messaging with your care team, provider-managed dose adjustments and quarterly labs are included at no extra cost. Your monthly price does not change as your dose is titrated.
Compare all four GLP-1 options side by side, or start your treatment.
What is Pomegranate?
Pomegranate is a telehealth platform offering compounded semaglutide and compounded tirzepatide for weight management, alongside a broader menu.
That menu is genuinely wide. It includes Contrave and metformin, both FDA-approved medications, plus NAD+, sermorelin, glutathione and lipotropic injections, and compounds for men's and women's health. If you want options beyond a GLP-1, that breadth is a real strength.
Its billing model is also distinctive and worth crediting. There is no monthly membership fee. You pay for the consultation and then for each medication order, which suits people who dislike recurring platform charges. Pomegranate also lets patients choose among several partner pharmacies at the same flat rate, which is unusual and gives you a say in who fills your prescription.
Delivery is described as fast and discreet at no extra cost. Support runs Monday to Friday from 7am to 10pm ET, and weekends from 8am to 5pm ET. Its site does not display a LegitScript certification, so we list that row as not publicly listed rather than making any claim either way.
Medications: what each platform offers
Both platforms work with the same drug class. Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GLP-1 and GIP agonist. These ingredients form the basis of FDA-approved brands and are widely studied for weight management. For background, see the NIH NIDDK overview and the FDA announcement on tirzepatide for weight management.
Pomegranate offers compounded semaglutide and compounded tirzepatide as injections. Its published catalog does not list an oral or sublingual GLP-1, and it does not list a microdosed protocol. Its non-GLP-1 options give providers more to work with if a GLP-1 is not appropriate for you.
TelosRX offers injectable semaglutide and injectable tirzepatide, plus needle-free oral tirzepatide and a microdosed tirzepatide protocol for people who want to ease in at a lower dose. Compounded medications from either platform are not FDA-approved and have not been evaluated by the FDA for safety, efficacy or quality.
Key takeaway: Pomegranate charges $75 up front for a live consultation before you know whether you qualify, and that fee is not refunded if you are not approved. TelosRX reviews you asynchronously and charges nothing unless you are approved.
Pricing and transparency
TelosRX prices by monthly plan, with the visit, medication, shipping, labs and support included:
- Semaglutide, injectable: as low as $99/month, down from $299
- Microdosed tirzepatide: as low as $116/month, down from $279
- Oral, needle-free tirzepatide: as low as $129/month
- Standard injectable tirzepatide: as low as $139/month, down from $399
That figure does not move when your dose does. Pomegranate lists compounded semaglutide from $119 a month and compounded tirzepatide from $179 a month, held flat across its pharmacy options. Holding one rate regardless of which pharmacy fills the script is a fair and transparent touch.
On top of the medication sits the $75 intake fee for first-time GLP-1 patients. If you are approved, that $75 is credited toward your first month. If you are not approved, it is not refunded. That is the single biggest practical difference between the two services, and it is worth understanding before you start.
Eligibility at Pomegranate generally means a BMI of 27 or above with a related condition, or 30 or above without one. Current GLP-1 users at a lower BMI may still be reviewed for maintenance dosing.
Neither platform bills insurance, and TelosRX plans are FSA and HSA eligible. Start your intake to see your TelosRX plan in minutes.
How the process works
This is the clearest split between the two.
TelosRX is a guided, fully asynchronous program. The intake takes about five minutes. A US-licensed provider reviews it without an appointment, typically within hours, and approved medication ships with free 48-hour delivery. If you are not approved, you pay nothing.
Pomegranate uses a three-step journey: an assessment, a provider review, then delivery. For first-time GLP-1 patients, that provider review takes the form of a live telehealth consultation covered by the $75 fee. Some people prefer that. Speaking to a clinician before starting a new medication is a reasonable thing to want, and Pomegranate builds its process around it.
Neither platform prescribes automatically. Any medication is subject to medical approval by a licensed provider. Begin your TelosRX intake to see if you qualify.
Support and ongoing care
TelosRX includes unlimited messaging with your care team, provider-managed dose adjustments and quarterly labs in every plan. Because pricing is flat, a dose increase is a clinical decision rather than a billing one.
Pomegranate offers support across long weekday hours and shorter weekend hours. On labs, its position is case by case: providers may ask for recent results from the past 12 months rather than including testing as standard. Because there is no membership fee, ongoing costs stay tied to what you actually order, which some people will prefer to a bundled plan.
Safety and medical oversight
TelosRX is LegitScript-certified. Pomegranate does not display a LegitScript certification on its site, so we make no claim in either direction. If certification matters to you, ask the platform directly and verify it yourself.
Both services route prescriptions through licensed US pharmacies and require a provider to review before anything is dispensed.
GLP-1 medications are not right for everyone. Providers screen for issues including a personal or family history of medullary thyroid cancer, pancreatitis and pregnancy. Side effects are most often digestive, especially early on, and typically ease with gradual dose titration.
Share your full medical history during intake on either platform, since approval is subject to medical review and is not guaranteed.
Which service is right for you?
Best if you want no appointment and no upfront risk: a five-minute asynchronous intake, nothing owed unless you are approved, a lower monthly price, needle-free and microdosed options, and quarterly labs included.
Best if you actively want a live consultation before starting, like choosing which pharmacy fills your prescription, prefer paying per order with no membership, or want non-GLP-1 options such as Contrave.
Pomegranate offers real strengths: pharmacy choice, no recurring membership and a wider medication menu. If you would rather not schedule a call, not pay before you know whether you qualify, and want a lower monthly price with labs included, TelosRX is the more straightforward pick.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is a LegitScript-certified telehealth service. Medications are compounded by licensed US pharmacies, and every prescription is subject to medical approval by a licensed provider.
Does Pomegranate charge a fee before you are approved?
Yes. First-time GLP-1 patients pay a $75 intake fee covering a live telehealth consultation. If you are approved, it is credited toward your first month of medication. If you are not approved, it is not refunded. TelosRX charges nothing if you are not approved.
How much does TelosRX cost compared to Pomegranate?
TelosRX plans are as low as $99 a month for semaglutide, $116 for microdosed tirzepatide, $129 for oral tirzepatide and $139 for standard injectable tirzepatide, with the visit, medication, shipping, labs and support included. Pomegranate lists compounded semaglutide from $119 a month and compounded tirzepatide from $179 a month, plus the $75 intake fee for new GLP-1 patients.
Is Pomegranate LegitScript certified?
Pomegranate does not display a LegitScript certification on its public website, so its status is not publicly listed. That is not the same as being uncertified. TelosRX is LegitScript-certified.
Does either service offer a needle-free GLP-1?
TelosRX offers oral, sublingual tirzepatide as a needle-free alternative to injections, plus a microdosed tirzepatide protocol. Pomegranate does not list a needle-free oral or sublingual GLP-1 on its site.
Who is Pomegranate best for?
Pomegranate suits someone who wants to speak with a provider before starting, values choosing among partner pharmacies, prefers paying per order rather than a membership, and may want non-GLP-1 options such as Contrave or metformin. If you want a fully asynchronous start with no upfront fee, TelosRX is the closer fit.
TelosRX is LegitScript-certified. Compounded medications from either platform are not FDA-approved and have not been evaluated by the FDA for safety, efficacy or quality. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service. Pomegranate details, including pricing, fees, catalog and policies, were checked against its public website and published reviews in July 2026 and may change.
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