Choosing between TelosRX and Refills for GLP-1 weight loss comes down to pricing clarity, needle-free flexibility, and clinical support depth. TelosRX starts from $49 a month and offers oral options; Refills covers weight loss alongside hair, sexual health, and mental wellness in one platform across all 50 states.
For the lowest entry price, needle-free options, and dedicated GLP-1 clinical support, TelosRX is the more focused choice. Refills suits people who want weight loss as part of a broader multi-condition telehealth platform.
Start your intake →Quick comparison: TelosRX vs Refills
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed.
What is TelosRX?
TelosRX is an online-first, LegitScript-certified telehealth pharmacy focused on GLP-1 weight management. It offers compounded tirzepatide and semaglutide, along with needle-free alternatives that are not available at most weight-loss telehealth providers.
The service is fully asynchronous. You complete a short online intake, and a US-licensed provider reviews it — often within hours. No appointment is needed. If approved, medication ships free with 48-hour delivery from licensed US compounding pharmacies. You can message your care team at any time, receive dose adjustments as needed, and access quarterly labs. All pricing is listed upfront, and there are no membership fees.
What is Refills?
Refills is an online telehealth platform that offers personalized health solutions from licensed providers across all 50 US states. Its categories span weight loss, hair care, sexual health, and mental wellness — positioning it as a multi-condition platform rather than a GLP-1 specialist.
Weight loss, including GLP-1 medications such as tirzepatide and semaglutide, appears to be a primary offering based on publicly available information. The platform operates with online provider review, and its full pricing and support details are gated behind an intake flow. For people who are managing several health goals at once — weight, hair, or mood — the breadth of Refills can be a genuine advantage.
Medications: what each program offers
Both programs work in the same drug class. Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GLP-1 and GIP agonist. These are the active ingredients behind FDA-approved brands like Wegovy and Zepbound, which are used for chronic weight management. For more background, see the NIH NIDDK overview of prescription weight-loss medications and the FDA announcement on tirzepatide for weight management.
The compounded versions of these medications — offered by programs like TelosRX — are not FDA-approved. They are prepared at licensed US compounding pharmacies under federal compounding regulations.
TelosRX distinguishes itself with oral tirzepatide — a needle-free option that dissolves under the tongue — and a lower-dose microdosed tirzepatide plan built for gradual titration. Refills offers compounded GLP-1s based on publicly available information, though its full medication menu is confirmed during intake.
Key takeaway: TelosRX is a GLP-1 specialist with needle-free options and published pricing from $49 a month. Refills covers weight loss alongside other health categories, which suits people managing multiple conditions — though its pricing and full medication list require completing an intake.
Pricing and transparency
This is one of the clearest differences between the two services.
TelosRX lists every plan before you sign up:
- From $49 a month — microdosed tirzepatide, 12-month plan
- $99 your first month — standard tirzepatide, 12-month plan
- $145, $199, or $399 first month — 6-month, 3-month, or single-month plans
HSA and FSA payments are accepted, and there are no membership fees. Cancel at any time.
Refills does not appear to publish pricing publicly on its website. Based on publicly available information, pricing is revealed after completing an intake — which means comparison shopping requires going through their onboarding flow. This is not unusual in telehealth, but it does make side-by-side cost comparisons harder for prospective patients.
If pricing transparency matters to you at the start, TelosRX's intake shows exact plan costs before you commit.
How the process works
TelosRX is fully asynchronous. You complete a short online intake — no appointment, no waiting room. A licensed provider reviews your health history, often within hours. If approved, medication ships free with 48-hour delivery from licensed US compounding pharmacies. Any prescription is subject to medical approval by a licensed provider.
Refills follows a similar online model: you complete intake through their platform, a licensed provider reviews your information, and medication is sent if appropriate. The full detail on provider-review timelines and shipping speed is confirmed during intake. The platform is available across all 50 states, which is the same coverage as TelosRX.
Coaching and ongoing support
TelosRX includes care-team messaging for questions and concerns, dose adjustments as your body responds to treatment, and quarterly labs to track your health markers over time. These are included as part of your plan — no extra fees for clinical check-ins.
Refills offers provider-reviewed care as part of its platform. Given its multi-category scope (weight loss, hair, sexual health, mental wellness), the support model may vary by condition. Full details on ongoing clinical touchpoints and check-in frequency for weight loss specifically are gated behind the intake process.
For people who want defined clinical milestones — regular labs, messaging access, dose titration guidance — TelosRX's published support structure is a genuine advantage.
Safety and medical oversight
Neither service prescribes automatically. Both gate medication behind a licensed provider review, which is the appropriate standard for GLP-1 medications.
GLP-1 medications are not suitable for everyone. Providers screen for contraindications including a personal or family history of medullary thyroid cancer, pancreatitis, pregnancy, and certain other conditions. Side effects — particularly nausea and digestive changes — are common during the initial titration phase.
TelosRX includes quarterly labs and ongoing care-team access to flag and address concerns. Share your complete medical history during intake, since every prescription is subject to medical approval by a licensed provider — approval is not guaranteed.
Which service is right for you?
Best for people who want a dedicated GLP-1 program with published pricing from $49/mo, needle-free options, quarterly labs, and LegitScript-certified care — all without a membership fee.
Best for people managing multiple health goals at once — weight loss alongside hair care, sexual health, or mental wellness — who prefer a single platform for several conditions.
For people focused specifically on GLP-1 weight management with full pricing visibility and needle-free flexibility, TelosRX is the more focused option. If managing several health categories through one provider is the priority, Refills is worth exploring.
Frequently Asked Questions
Is TelosRX a legitimate telehealth provider?
Yes. TelosRX is LegitScript-certified, which means it has been independently verified against standards for legitimate online healthcare providers. Medications are compounded at licensed US compounding pharmacies, and every prescription is subject to medical approval by a licensed provider. Approval is not guaranteed.
Does Refills offer GLP-1 weight loss medications?
Yes. Based on publicly available information, Refills offers weight loss as one of its service categories, with tirzepatide and semaglutide among its offerings. Refills is a multi-category telehealth platform that also covers hair care, sexual health, and mental wellness — which distinguishes it from GLP-1 specialist providers like TelosRX.
Are the compounded GLP-1 medications FDA-approved?
No. Compounded tirzepatide and semaglutide are not FDA-approved. They are prepared at licensed US compounding pharmacies under federal compounding regulations. FDA-approved brand medications like Wegovy and Zepbound contain the same active ingredients but go through FDA's drug approval process separately.
How much does TelosRX cost for GLP-1 treatment?
TelosRX publishes all pricing upfront. Microdosed tirzepatide starts from $49 a month on a 12-month plan. Standard tirzepatide is $99 for the first month on a 12-month plan, or $145, $199, or $399 first month for 6-month, 3-month, or single-month plans. HSA and FSA are accepted. Refills does not appear to publish pricing publicly — costs are confirmed during their intake process.
Can I do a TelosRX intake without scheduling an appointment?
Yes. TelosRX is fully asynchronous. You complete a short online intake at any time, and a US-licensed provider reviews your information — typically within hours. There is no appointment to book, no video call required, and no waiting room. If approved, medication ships free with 48-hour delivery. Any prescription is subject to medical approval by a licensed provider.
What makes TelosRX different from Refills?
TelosRX specializes exclusively in GLP-1 weight management and offers features not common elsewhere: needle-free oral tirzepatide, a microdosed titration plan starting at $49 a month, LegitScript certification, quarterly labs, and fully transparent pricing before you sign up. Refills takes a broader approach, covering multiple health categories in one platform — a genuine advantage for people managing more than one condition.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
Start your private evaluation at TelosRX.