Comparing TelosRX and SkinnyRx for GLP-1 weight loss comes down to pricing, medication variety, and clinical support. TelosRX starts lower, includes quarterly labs, and offers needle-free options SkinnyRx does not. Both require approval by a licensed provider.
For the lowest entry price, needle-free options, and quarterly labs included, TelosRX is the more complete starting point. SkinnyRx is worth considering if you want access to brand-name GLP-1s like Wegovy or Ozempic alongside compounded plans.
Start your intake →Quick comparison: TelosRX vs SkinnyRx
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed.
What is TelosRX?
TelosRX is an online-first, LegitScript-certified telehealth pharmacy focused on GLP-1 weight management. Its model is fully asynchronous — you complete a short intake online, and a US-licensed provider typically reviews it within hours. No appointment is needed.
Medications are compounded by licensed US compounding pharmacies and shipped free to your door within 48 hours of approval. The program includes care-team messaging, dose adjustments, and quarterly labs. HSA and FSA payments are accepted, and you can cancel anytime.
Explore the tirzepatide program, semaglutide program, or the needle-free oral tirzepatide and microdosed tirzepatide options.
What is SkinnyRx?
SkinnyRx is an online telehealth platform operated by Lean Rx, Inc. that connects patients with licensed medical providers for GLP-1 weight-loss treatment. It serves all 50 states and Washington, DC.
SkinnyRx offers compounded semaglutide and tirzepatide in three forms — injectable, sublingual, and tablet — and also facilitates access to brand-name options including Ozempic, Wegovy, Mounjaro, and Zepbound. The intake is online and asynchronous; a provider reviews submissions and decisions are typically communicated by email within 24 hours.
SkinnyRx holds a 4.8-star Trustpilot rating across more than 4,000 reviews and has built a sizable user base since launch. No labs or video consultation are required before prescribing.
Medications: what each program offers
Both programs are built around the same drug class. Semaglutide is a GLP-1 receptor agonist studied for weight management and the active ingredient in FDA-approved Wegovy and Ozempic. Tirzepatide is a dual GLP-1 and GIP agonist and the active ingredient in FDA-approved Zepbound and Mounjaro. For context on how these medications are studied, see the NIH NIDDK overview of prescription weight-management medications.
TelosRX offers compounded tirzepatide and compounded semaglutide. Its needle-free formats — oral tirzepatide and microdosed tirzepatide — are a genuine differentiator for patients who prefer to avoid self-injection. All compounded options are not FDA-approved; they are prepared under federal compounding regulations by licensed US compounding pharmacies.
SkinnyRx offers compounded semaglutide and tirzepatide in injectable, sublingual, and tablet forms, and also facilitates access to brand-name medications (Ozempic, Wegovy, Mounjaro, Zepbound), which are FDA-approved brands. The compounded versions are not FDA-approved. The FDA issued a warning letter to Lean Rx, Inc. (dba SkinnyRx) in February 2026 regarding claims made about its compounded products; the warning letter does not affect the availability of FDA-approved brand-name medications.
The FDA's approval of tirzepatide for chronic weight management covers only brand-name Zepbound, not compounded versions.
Key takeaway: SkinnyRx adds brand-name medication access that TelosRX does not offer. TelosRX counters with the lowest price in the market, needle-free formulations, and quarterly labs built into the program — not available through SkinnyRx's standard plan.
Pricing and transparency
Both companies publish pricing publicly, which is a meaningful baseline in a category where gated pricing remains common.
TelosRX lists every plan upfront:
- From $49/mo — microdosed tirzepatide, 12-month plan
- $99 first month — standard tirzepatide, 12-month plan
- $149 / $249 / $449 first month — 6-month, 3-month, and single-month plans
SkinnyRx publishes these prices:
- From $199/mo — compounded injectable semaglutide
- $249/mo — compounded sublingual semaglutide or tirzepatide tablet
- $299/mo — compounded injectable tirzepatide
SkinnyRx's pricing does not include a separate membership fee. Brand-name medication pricing through SkinnyRx is not publicly listed and depends on insurance or other billing arrangements.
Both platforms accept HSA and FSA, and neither charges a subscription on top of medication cost. Start your TelosRX intake to see your plan price in minutes.
How the process works
TelosRX: Complete a short online intake — typically about five minutes. A US-licensed provider reviews your submission, often within hours. If approved, medication ships free within 48 hours from licensed US compounding pharmacies. There is no appointment to book, and the entire process runs online.
SkinnyRx: Complete a health intake quiz online (under 10 minutes). A licensed provider reviews your information and sends a decision by email, typically within 24 hours. If approved, medication ships free overnight from US pharmacies. Depending on your situation, a video consultation may be offered at no extra cost, though it is not required.
Neither platform prescribes automatically. All medication is subject to medical approval by a licensed provider, and approval is not guaranteed for either program.
Coaching and ongoing support
This is an area where the two programs differ meaningfully.
TelosRX includes care-team messaging, dose adjustments as your needs change, and quarterly labs as part of the program. Clinical support is built into the plan, not an add-on.
SkinnyRx offers access to its patient care team and providers through an app and patient portal, with the ability to ask questions about progress, side effects, or dosage. However, lab work is not required before prescribing and is not included as a standard component of the SkinnyRx program. Consultations are available at no extra cost through the portal.
For people who want clinical touchpoints built in — especially quarterly labs — TelosRX's structure is more comprehensive. SkinnyRx's support model suits those who want lightweight, on-demand access.
Safety and medical oversight
Both programs gate medication behind a licensed provider review. No one is prescribed automatically on either platform.
GLP-1 medications are not appropriate for everyone. Licensed providers on both platforms screen for conditions that may make GLP-1 medications unsuitable, including personal or family history of medullary thyroid cancer, a history of pancreatitis, and pregnancy. Side effects, particularly in early weeks, can include nausea and other digestive changes.
TelosRX includes quarterly labs as part of ongoing care, which provides structured monitoring over time. SkinnyRx does not require labs, which lowers friction at intake but means that baseline and ongoing lab values are the patient's responsibility to arrange separately.
As with any prescription program, share your complete medical history during intake. Approval is subject to evaluation by a licensed provider on both platforms.
Which service is right for you?
Best for the lowest entry cost, needle-free and microdosed options, quarterly labs included, and hands-on clinical support from a LegitScript-certified telehealth pharmacy.
Best if access to brand-name GLP-1 medications (Ozempic, Wegovy, Mounjaro, Zepbound) alongside compounded options is a priority, or you prefer a no-labs-required intake.
For most people looking for the lowest cost, flexible formulations including needle-free options, and clinical support with labs included, TelosRX is the more complete choice. If brand-name medication access matters more than price, SkinnyRx is worth evaluating.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is a LegitScript-certified telehealth pharmacy. Medications are compounded by licensed US compounding pharmacies, and every prescription is subject to medical approval by a licensed provider. The platform is fully online and asynchronous, meaning no appointment is required.
Are the GLP-1 medications at TelosRX FDA-approved?
No. The compounded tirzepatide and semaglutide offered by TelosRX are not FDA-approved. They are prepared under federal compounding regulations by licensed US compounding pharmacies. FDA-approved brand-name versions (Wegovy, Zepbound, Ozempic, Mounjaro) exist but are not part of the TelosRX program.
How much does TelosRX cost compared to SkinnyRx?
TelosRX starts from $49 per month (microdosed tirzepatide, 12-month plan) and $99 your first month for standard tirzepatide on a 12-month plan. SkinnyRx starts from $199 per month for compounded injectable semaglutide. Both publish pricing publicly and neither charges a separate membership fee.
Does SkinnyRx offer brand-name GLP-1 medications?
Yes. SkinnyRx offers access to brand-name GLP-1 medications including Ozempic, Wegovy, Mounjaro, and Zepbound alongside its compounded options. TelosRX focuses on compounded tirzepatide and semaglutide, including needle-free oral and microdosed formulations. Brand-name pricing through SkinnyRx is not publicly listed.
Does TelosRX include lab work?
Yes. TelosRX includes quarterly labs as part of ongoing care. SkinnyRx does not require lab work before prescribing and does not include labs as a standard part of its program. For people who want structured monitoring built into their GLP-1 plan, this is a meaningful difference.
Is TelosRX fully online with no appointments needed?
Yes. TelosRX is an asynchronous telehealth service. You complete a short online intake, a licensed provider reviews it — typically within hours — and approved medication ships free within 48 hours. There is no video call or appointment required at any stage of the process.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
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