Comparing TelosRX and Trimi (also marketed as Trimi Health, at trytrimi.com) comes down to pricing transparency and medication format. Both run fully online with compounded GLP-1 medication, but they differ in how clearly pricing is shown, what needle-free options exist, and what's included in ongoing care.
For upfront pricing on every plan, needle-free oral and microdosed tirzepatide options, and LegitScript certification, TelosRX is the more transparent choice. Trimi fits if you want a straightforward injectable-only semaglutide or tirzepatide plan with tiered pricing shown on its treatment pages and a stated money-back promise.
Start your intake →Quick comparison: TelosRX vs Trimi
Compounded medications referenced in this comparison are not FDA-approved. They are prepared under state and federal compounding regulations for individual patients, and this comparison covers each company's compounded programs — not the FDA-approved, patent-protected branded drugs that share the same active ingredients. Any prescription is subject to review and approval by a licensed provider, and approval is never guaranteed.
What is TelosRX?
TelosRX is a LegitScript-certified, online-first telehealth provider focused on GLP-1 weight management. The service offers compounded tirzepatide — including standard, oral, and microdosed formats — alongside compounded semaglutide.
The entire process is asynchronous. A roughly five-minute intake questionnaire is reviewed by a licensed provider, often within hours, with no mandatory video visit or scheduled appointment required. If approved, medication ships free within 48 hours.
TelosRX is cash-pay and FSA/HSA-eligible, with every plan tier priced upfront on its product pages. Ongoing care includes unlimited care-team messaging, quarterly labs, and the ability to cancel anytime. You can start your intake in minutes.
What is Trimi?
Trimi — also marketed as Trimi Health at trytrimi.com — is an online telehealth platform offering compounded semaglutide and compounded tirzepatide. According to its site, every prescription is reviewed and signed by a state-licensed provider through its clinical network, and medication is compounded by 503A pharmacies, including VialsRx and GreenwichRx.
Trimi's model is asynchronous: patients complete a short online health assessment, and the company states a licensed provider typically reviews it within 24 hours. We didn't find a mandatory video visit referenced on the pages we reviewed. Trimi's site also displays a LegitScript healthcare-merchant verification seal, though we were not able to independently confirm current certification status beyond what's shown on their pages.
Pricing is tiered by commitment length on Trimi's treatment pages, with lower monthly rates tied to longer plans (annual, six-month, quarterly, and month-to-month). The company also advertises free shipping and a six-month money-back promise, subject to terms outlined on its site.
Medications: what each program offers
Both companies work with the same two GLP-1 medication classes. Semaglutide is a GLP-1 receptor agonist; tirzepatide is a dual GLP-1/GIP receptor agonist. These are the active ingredients behind FDA-approved branded drugs such as Wegovy and Zepbound — but the compounded versions offered by TelosRX and Trimi are not FDA-approved, and individual results vary.
TelosRX offers the widest format menu, including needle-free oral tirzepatide and a microdosed option, in addition to standard tirzepatide and semaglutide injections. Trimi's published pages describe injectable compounded semaglutide and tirzepatide only, with no oral or microdosed format listed. For general background on this medication class, see the NIH NIDDK overview and the FDA's announcement on tirzepatide for chronic weight management.
Key takeaway: Both companies run an asynchronous, online-first model with compounded GLP-1 medication. TelosRX publishes every price and tier upfront and offers needle-free oral and microdosed tirzepatide formats; Trimi's pricing is tiered by commitment length on its treatment pages and is currently limited to injectable semaglutide and tirzepatide.
Pricing and transparency
TelosRX lists every plan price before you sign up:
- From $116/mo — microdosed tirzepatide
- From $139/mo — standard tirzepatide
Trimi lists tiered pricing directly on its treatment pages. Based on our review, tirzepatide ranges from roughly $125/mo on an annual plan up to $235/mo billed monthly, and semaglutide ranges from roughly $99/mo on an annual plan up to $175/mo billed monthly, with quarterly and six-month tiers in between. Trimi states its pricing is flat regardless of dose and includes medication, provider review, and shipping. As with any subscription-style program, confirm the exact tier and total billed amount directly on Trimi's site before enrolling.
How the process works
TelosRX's intake takes about five minutes. A licensed provider reviews it asynchronously — often within hours — and approved medication ships free within 48 hours. There's no appointment to schedule.
Trimi's process follows a similar shape: complete an online health assessment, and the company states a provider reviews it within 24 hours. If approved, medication ships, with Trimi's site referencing free shipping and delivery commonly reported within a few days.
Neither program prescribes automatically. Every order is subject to review and approval by a licensed provider, and approval is never guaranteed.
Guarantees and ongoing support
TelosRX includes unlimited care-team messaging, dose adjustments, and quarterly labs for the duration of treatment, with the ability to cancel anytime and no long-term contract required.
Trimi advertises unlimited provider messaging, dose adjustments, and the ability to cancel anytime with no stated cancellation fee; some of its pages also reference the option to pause a plan for up to three months. Trimi additionally promotes a six-month money-back guarantee for patients who follow their plan as prescribed and don't see results, though specific terms and conditions apply — confirm current details directly on Trimi's site before enrolling. We did not find a mention of routine lab monitoring in Trimi's published materials.
Safety and medical oversight
GLP-1 medications aren't appropriate for everyone. Licensed providers typically screen for factors such as a personal or family history of medullary thyroid carcinoma or MEN 2, pancreatitis, and pregnancy before approving treatment. Gastrointestinal side effects — nausea, constipation, and appetite changes — are common, particularly during dose titration. Both TelosRX and Trimi gate access behind a licensed-provider review, and neither can guarantee approval or outcomes; individual results vary based on a range of personal health factors.
Which service is right for you?
Best for anyone who wants every price listed upfront, needle-free oral or microdosed tirzepatide formats, and ongoing quarterly labs from a LegitScript-certified provider.
Best if you want a straightforward injectable-only semaglutide or tirzepatide plan, with tiered pricing shown on the treatment page and a stated money-back promise.
For most people who want clear costs upfront and needle-free options, TelosRX is the more straightforward choice. If a flat-rate, injectable-only program with a stated guarantee appeals to you, Trimi is worth a look.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is a LegitScript-certified telehealth pharmacy. Medications are compounded by licensed US pharmacies, and every prescription is subject to review and approval by a licensed provider.
Are the medications FDA-approved?
No. The compounded tirzepatide and semaglutide offered by TelosRX and Trimi are not FDA-approved. They're prepared under state and federal compounding regulations for individual patients. FDA-approved branded versions of these active ingredients include Wegovy and Zepbound.
How much does TelosRX cost vs Trimi?
TelosRX publishes every tier upfront: microdosed tirzepatide from $116/mo, and standard tirzepatide from $139/mo. Based on our review of Trimi's site, its tirzepatide ranges from roughly $125/mo (annual) to $235/mo (monthly), and semaglutide from roughly $99/mo (annual) to $175/mo (monthly).
Is TelosRX fully online?
Yes. TelosRX is online-first and asynchronous. You complete a short intake, a licensed provider reviews it, and approved medication ships to your door — no scheduled video visit required.
Can I switch from Trimi to TelosRX?
Yes. You can start a new TelosRX intake at any time, regardless of your current or past program. A licensed provider will review your health history and goals before any medication is approved.
How fast is provider review?
TelosRX's licensed providers often review completed intakes within hours. Trimi's site states a similar asynchronous review process, with approval reported within 24 hours.
TelosRX is LegitScript-certified. Compounded medications referenced above are not FDA-approved and are prepared under state and federal compounding regulations for individual patients. Any prescription is subject to evaluation and approval by a licensed provider, and approval is never guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service. Visit TelosRX to learn more, or begin your intake today.