Choosing between TelosRX and TrimRX for GLP-1 weight loss comes down to what you value. TelosRX publishes every plan price upfront and runs a fast, fully online process. TrimRX bundles compounded GLP-1 medication into a simple month-to-month plan but reveals pricing only after a quiz. Both require approval by a licensed provider.
For transparent pricing and a fast online start, TelosRX is the simpler choice. TrimRX fits if you want an all-inclusive, month-to-month plan and don't mind getting your quote through a quiz.
Start your intake →Quick comparison: TelosRX vs TrimRX
Compounded medications are not FDA-approved. Any prescription is subject to medical approval by a licensed provider, and approval is not guaranteed.
What is TelosRX?
TelosRX is an online-first, LegitScript-certified telehealth pharmacy. It focuses on GLP-1 weight management with compounded tirzepatide and semaglutide.
The service is asynchronous. You finish a short intake online, and a US-licensed provider reviews it, usually within a few hours. There is no appointment to book.
Medications are compounded by licensed US pharmacies and shipped to your door. You can message your care team anytime, and pricing is published upfront, so there are no surprises.
Browse the tirzepatide and semaglutide options, or start your treatment.
What is TrimRX?
TrimRX is a direct-to-consumer telehealth platform for compounded GLP-1 weight management. You complete an online intake, a US-licensed clinician reviews your history, and an FDA-registered compounding pharmacy ships your medication.
TrimRX offers compounded semaglutide and compounded tirzepatide. It charges no membership fee, and its plans are month-to-month. There are no required telehealth appointments and no routine lab work. Most people receive medication within five to seven days.
Support runs through the patient portal with unlimited provider check-ins, plus phone support seven days a week. TrimRX keeps things streamlined: there is no app and no dedicated coach. If you want a no-frills, all-inclusive plan, TrimRX leans into that.
Medications: what each program offers
Both programs center on the same drug class. Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GLP-1 and GIP agonist.
These ingredients are studied for weight management and are the basis of FDA-approved brands like Wegovy and Zepbound. The compounded versions offered by both TelosRX and TrimRX are not FDA-approved.
TelosRX also offers needle-free oral tirzepatide and a microdosed option, which TrimRX does not list. For background, see the NIH NIDDK overview and the FDA note on tirzepatide for weight management.
Key takeaway: TelosRX lists every plan price before you sign up. With TrimRX, you see your price only after completing a quiz.
Pricing and transparency
This is the clearest difference. TelosRX lists every plan price before you sign up.
- From $49 a month — microdosed tirzepatide, 12-month plan
- $99 your first month — standard tirzepatide, 12-month plan
- $145, $199, or $399 first month — 6-month, 3-month, or single-month plans
TrimRX publishes all-inclusive rates but reveals your exact quote through its assessment quiz. Reported pricing starts around $174 a month for semaglutide on a 12-month supply and around $283 a month for tirzepatide, rising for shorter plans and higher doses. Both accept FSA and HSA.
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How the process works
TelosRX is built for speed. The intake takes about five minutes. A licensed provider reviews it asynchronously, often within hours, and approved medication ships with free 48-hour delivery.
TrimRX works similarly online. You complete an intake quiz, a clinician reviews it, and an FDA-registered pharmacy ships your medication, often within five to seven days. There are no required video visits.
Neither prescribes automatically. Any medication is subject to medical approval by a licensed provider. When you are ready, start your online visit and a provider will review your history.
Coaching and ongoing support
TrimRX keeps support clinical and direct. You get unlimited check-ins with your provider through the portal, plus phone support seven days a week. It does not bundle a coach, an app, or routine labs.
TelosRX also keeps support focused. You get unlimited messaging with your care team, dose adjustments as your body changes, and quarterly labs included.
One is not strictly better. TrimRX suits people who want a no-frills plan with phone access. TelosRX suits people who want responsive messaging plus built-in labs and dose management.
Safety and medical oversight
Both programs gate medication behind a licensed provider. No one is prescribed automatically.
GLP-1 medications are not for everyone. Providers screen for issues like a personal or family history of medullary thyroid cancer, pancreatitis, and pregnancy. Side effects can include nausea and digestive changes, especially early on.
TelosRX includes quarterly labs and care-team messaging, so concerns get flagged. Share your full history during intake, since approval is subject to medical review.
Which service is right for you?
Best for transparent pricing, a fast async start, and a streamlined, medication-first program from a LegitScript-certified pharmacy.
Best for an all-inclusive, month-to-month plan with unlimited provider check-ins and seven-day phone support.
For most people who want clear costs and a simple online start, TelosRX is the more straightforward choice.
Frequently Asked Questions
Is TelosRX legitimate?
Yes. TelosRX is a LegitScript-certified telehealth pharmacy. Medications are compounded by licensed US pharmacies, and every prescription is subject to medical approval by a licensed provider. You complete a short online intake, and a provider reviews your history before anything is approved.
Are the GLP-1 medications FDA-approved?
The compounded tirzepatide and semaglutide offered by both TelosRX and TrimRX are not FDA-approved. They are prepared under federal compounding regulations for individual prescriptions. The same active ingredients appear in FDA-approved brands like Wegovy and Zepbound, but the compounded versions are a separate category.
How much does TelosRX cost compared to TrimRX?
TelosRX publishes its pricing upfront. GLP-1 plans start from $49 a month for microdosed tirzepatide on the 12-month plan, with standard tirzepatide from $99 your first month. TrimRX shows its all-inclusive quote after a quiz, with reported rates starting around $174 a month for semaglutide.
Is TelosRX fully online?
Yes. TelosRX is online-first and asynchronous. You finish a short intake, a licensed provider reviews it, usually within hours, and approved medication ships to you. No appointment is required, and you can message your care team anytime through the portal.
Can I switch from TrimRX to TelosRX?
Many people compare programs before deciding. You can start a new TelosRX intake at any time. A provider reviews your history, current medication, and goals before any new prescription is approved, so be ready to share what you are taking now.
How fast is provider review at TelosRX?
Intake review is asynchronous and usually happens within a few hours. If approved, medication ships with free 48-hour delivery. Timing can vary by individual case, and approval is never guaranteed because every order is subject to medical review.
TelosRX is LegitScript-certified. Compounded medications are not FDA-approved and are prepared under federal compounding regulations. Approval is subject to evaluation by a licensed provider; approval is not guaranteed. Individual results vary. TelosRX operates as an online-first, asynchronous telehealth service.
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